CITSens Bio

Product

Product

Online and in-situ measurement of glucose, glutamate and lactate.

 

Description

 

CITSens Bio is a system for online, in-situ measurement of glucose, glutamate and lactate in cell cultures.

 

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Performance characteristics

 

  • Online measurement directly in the culture flasks

  • Monitoring of sterility of the cell cultures and media

  • Optimized cultivation conditions

  • High throughput applications

  • Made for PAT (process analysis technique)

     

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Recording of measured values in real time


Real time analysis of measurements relevant to the process, takes place in the disposable reactor. This eliminates costly and risky sample taking which disturbs the cell system and could lead to contamination. With CITSens Bio, cell culture sterility is guaranteed at all times.

The CITSens Bio sensor, a screen printed electrode, is very easy to handle. The gamma sterilised sensor is delivered ready for use.

The sensor is connected to the CITSens Bio Beamer by a cable. The CITSens Bio Beamer is placed right next to the reactor system and incorporates a data acquisition unit as well as a transmitter for wireless transmission of the measured values of glucose, glutamate and lactate in g/I directly to a receiver. ZOMOFI® receives measurement data from up to 1,000 sensors and transfers these to the PC (RS232 or LAN).

Sensor with cap

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Technical Data

Technical data

 

Online and in-situ measurement of glucose, glutamate and lactate.

 

CITSens Bio Sensor

 

CITSens Bio Sensor Screen printed electrode with immobilized enzyme
Precision ± 1 mmol
Resolution

glucose:  0.1 mmol

glutamate:  0.5 mmol

lactate:  0.5 mmol

Detection limit (glucose, glutamate, lactate) 1 mmol
Longest cultivation time 200 h
Calibration 2 point calibration in situ
Dimensions

thickness:  approx. 150 µm

diameter at tip:  1 cm

length:  10 cm or 22 cm

(different lengths upon request)

Service life in continuous use 14 days
Shelf life 6 months at 5°C

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Radio transmitter CITSens BioBeamer

 

Technology active RFID
Frequency 2.4 - 2.483 GHz
Battery rechargeable batteries
Dimensions L x W x H:  85 x 46 x 16 mm

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Radio Receiver ZOMOFI

 

Technology active RFID
Frequency 2.4 - 2.483 GHz
Dimensions L x W x H:125 x 107 x 27 mm 
Weight 204 g
PC-connection

RS232

Network connection with integrated Lantronix WLAN/LAN module

Software 21CFR11 compliant

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